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Fig. 5 | BMC Microbiology

Fig. 5

From: In vivo competition and horizontal gene transfer among distinct Staphylococcus aureus lineages as major drivers for adaptational changes during long-term persistence in humans

Fig. 5

Model of the in vivo evolution and interactions of the CF S. aureus lineages from 1995 to 2008. The isolates within the airways are shown as colored circles; every lineage has its own color. Hypothetical isolates, which were not isolated but probably took place in the direct line of evolution, are depicted as dashed circles. Black arrows connect sequential isolates of the same lineage; dashed lines connect hypothetical isolates. Colored (+) and () indicate the acquisition or loss of genetic material. If genetic material was likely to be transferred from one lineage to another, dotted colored arrows show the assumed direction and the transferred material is listed. In case the origin was ambiguous, the transferred material is shown in brackets. In addition, the 25.7 kb DNA transposon (yellow line), the 30 kb plasmid (green circle), and the 14.2 kb DNA transposon (brown line) are shown. If applicable, boxes display in a pairwise comparison of consecutive isolates the number of differing synonymous (S), non-synonymous (N), or intergenic (I) SNPs, the number of insertions (In) and deletions (Del), and the dN/dS value. N/A, not applicable

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