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Table 3 SGHV-encoded orthologs of cellular genes: The protein families shown in this table were restricted to those that showed significant domain structural conservations. The proteins listed here have been described during the reporting of the genome sequences of the SGHVs [4,5,6]

From: Coevolution of hytrosaviruses and host immune responses

Protein Name GpSGHV ORF (ORF No.) Location in virus particle MdSGHV (ORF No.) Homology or description
Lecithine-cholesterol acyltransferase (T, P) 5 5 ICSVP £ 46 Pseudomonas sp.
D-3-phosphoglycerate dehydrogenase (T, P) 6 7 Tegument Clostridium ultunense
MAL7P1.132 (T, P) 8 9 ICSVP Plasmodium falciparum Str. 3D7
UDP-glucose-6 dehydrogenase (T) 13 16 Unknown Pseudobutyrivibrio ruminis
NADH ubiquinone oxidoreductase (T) 30 29 Virion protein Styphylococcal AgrD protein
Maltodextrin glycosyltransferase (T, P) 39 38 Tegument RGD-domain containing protein
Glutathione S-transferase (T, P) 48 46 Tegument 84 Pre-mRNA splicing factor
Cellular protein CBG22662 (T, P) 49 47 Tegument Coenorhabditis briggsae
Rhoptry protein kinase (T) 58 57 Plasmodium yolei Str. 17XNL
Signaling mucin HKR1 64 Xenopus (Silurana) tropicalis
RpoD protein (T) 66 59 Plasmodium falciparum
ECF transporter (T, P) 75 68 Envelop
Cellular protein PY00593 (T, P) 124 113 Nucleocapsid NaN Plasmodium yolei Str. 17XNL
Tail length tape-measure (T, P) 149 134 ICSVP Oenococcus phage phi9805
  1. Expression confirmed by transcriptomics (T) and proteomics only (P). Unmarked genes have no detectable transcripts or peptides; £ These proteins do not have specific localization and were designated as ‘infected cell-specific viral proteins (ICSVP)’ [6]