Table 2 Comparison of MdSGHV IAP with homologs reported in other viruses: The analysis revealed clustering of the IAPs from MdSGHV, ASFV and CIV. Compared to the other viruses analyzed, the domain architecture of MdSGHV, ASFV and CIV IAPs contained one BIR domain and an additional RING domain (compare the data in this table with Fig. 2)
From: Coevolution of hytrosaviruses and host immune responses
Virus | Sequence Name | GenBank Acc. No. | Length (aa) | BIR domain coordinates | RING domain coordinates |
|---|---|---|---|---|---|
Cydia pomonella granulovirus (CpGV) | ORF17 iap-3 | AIU36666.1 | 275 | 10–74; 111–176 | 224–269 |
Orgyia pseudotsugata multiple nucleopolyhedrovirus (OpMNPV) | IAP-3 | NP_046191.1 | 268 | 21–85; 114–179 | 217–262 |
IAP-1 | NP_046197.1 | 275 | 27–92; 129–194 | 223–269 | |
Spodoptera exigua multiple nucleopolyhedrovirus (SeMNPV) | IAP-3 | CDG72862.1 | 314 | 34–99; 157–222 | 263–308 |
Musca domestica SGHV (MdSGHV) | IAP | YP_001883406.1 | 142 | 12–77 | 92–136 |
Chilo/invertebrate iridescent virus (CIV/IIV-6) | 193R (BIRP) | NP_149656.1 | 208 | 40–109 | 159–203 |
Autographa californica nucleopolyhedrovirus (AcNPV) | IAP | NP_054056.1 | 286 | 32–97; 134–200 | 234–280 |
African swine fever virus (ASFV) | IAP | P0C9X4.1 | 224 | 32–93 | 94–224 |
IAP-homolog | NP_042727.1 | 224 | 32–93 | 94–224 | |
Buzura suppressaria nucleopolyhedrovirus (BusuNPV) | IAP-1 | AAC34373.1 | 276 | 15–79; 111–177 | 225–270 |
IAP-3 | YP_009001870.1 | 276 | 15–79; 111–177 | 225–270 | |
Epiphyas postvittana nucleopolyhedrovirus (EppoNPV) | IAP-3 | NP_203195.1 | 261 | 14–78; 104–169 | 210–255 |
Bombyx mori nucleopolyhedrovirus (BmNPV) | IAP-1 | NP_047432.1 | 292 | 32–97; 134–200 | 240–286 |