Fig. 3
From: Coevolution of hytrosaviruses and host immune responses
Phylogenetic analysis of the key RNAi pathway proteins in dipterans: a Clustering of the housefly and tsetse fly RNAi proteins with their homologs in the fruit fly and the malaria mosquito. b Domains of the three key RNAi pathway proteins, Ago-2, Dcr-2, R2D2, and c three of their main cofactors Spn-E, Pasha and Loqs. Purple circles indicate bootstrap support of >80%. The identities of the domains in the different irregular pentagon/hexagon shapes in Panels (b) and (c) in this figure are shown on top of each shape. Abbreviations: -PIWI, P-element Induced WImpy testis gene domain; PAY, PIWI-Argonaute-Zwille domains; dsRNABD/ dsRBD, double-stranded RNA-binding domain/motif; RNase-III, Ribonuclease III domain; DExH Box/Tudor, EAD/DEAH box helicases family protein domains; Rrsp5/WWP, rice root-specific promoter protein 5/Tryptophan-tryptophan-proline motif