Fig. 1From: The therapeutic potential of bacteriophages targeting gram-negative bacteria using Galleria mellonella infection modelImpact of single dose phage treatment on E. coli ec311, K. pneumoniae kp235 and E. cloacae el140 infection and survival rates of G. mellonella larvae. A single phage dose (104 PFU/mL) was injected at 0th hour after the larvae was pre-infected with 108 CFU/mL of bacteria. a Saline, phage and bacteria only control group larval survival. b Survival rates of the larvae infected with E. coli ec311 treated with single dose of Escherichia phage ECP311 (p = 0.0045). c Survival rates of the larvae infected with K. pneumoniae kp235 treated with single dose Klebsiella phage KPP235 (p = 0.0006). d Survival rates of larvae infected with E. cloacae el140 treated with Enterobacter phage ELP140 (p = 0.0052). The survival rates were plotted using the Kaplan-Meier method and log-rank test was used to analyze the difference in survival rates in GraphPad Prism 7.0. All phage treatment results were compared with the control. A statistically significant difference (p < 0.05) was observed using 10 worms per group on phage treatmentBack to article page