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Table 1 Antibiotic breakpoints for M. catarrhalis strains in EUCAST, CLSI and BSAC

From: β-Lactamase production and antibiotic susceptibility pattern of Moraxella catarrhalis isolates collected from two county hospitals in China

Antibiotics*

MICa/D-zoneb

EUCASTc

CLSId

BSACe

S

R

S

I

R

S

I

R

AMP

MIC(mg/L)

-#

-#

-#

-#

-#

≤1

> 1

AMC

MIC(mg/L)

≤1

>1

≤4

≥8

≤1

> 1

CXM

MIC(mg/L)

≤4

>8

≤4

8

≥16

≤1

2

> 2

CAZ

MIC(mg/L)

-#

-#

≤2

-#

-#

-#

-#

-#

FEP

MIC(mg/L)

≤4

>4

-#

-#

-#

-#

-#

-#

CIP

MIC(mg/L)

≤0.5

>0.5

≤1

-#

-#

≤0.5

> 0.5

ERY

MIC(mg/L)

≤0.25

>0.5

≤0.5

1–4

≥8

≤0.25

0.5

> 0.5

MEM

MIC(mg/L)

≤2

>2

-#

-#

-#

-#

-#

-#

TCY

D-zone(mm)

≥28

<25

≥29

25–28

≤24

≥22

≤21

CHL

D-zone(mm)

≥30

<30

-#

-#

-#

-#

-#

-#

SXT

D-zone(mm)

≥18

<15

≥13

11–12

≤10

≥12

≤11

  1. aMIC minimum inhibitory concentration, bD-zone diameter of inhibition zone, cEUCAST, European Committee on Antimicrobial Susceptibility Testing, dCLSI Clinical and Laboratory Standards Institute, eBSAC British Society for Antimicrobial Chemotherapy, *AMP ampicillin, AMC amoxicillin–clavulanic acid, CXM cefuroxime, CAZ ceftazidime, FEP cefepime, CIP ciprofloxacin, ERY eryciprofloxacin, MEM meropenem, TCY tetracycline, CHL chloramphenicol, SXT sulfamethoxazole–trimethoprim, # no breakpoints listed in the according criterion