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Table 1 Antibiotic breakpoints for M. catarrhalis strains in EUCAST, CLSI and BSAC

From: β-Lactamase production and antibiotic susceptibility pattern of Moraxella catarrhalis isolates collected from two county hospitals in China

Antibiotics* MICa/D-zoneb EUCASTc CLSId BSACe
S R S I R S I R
AMP MIC(mg/L) -# -# -# -# -# ≤1 > 1
AMC MIC(mg/L) ≤1 >1 ≤4 ≥8 ≤1 > 1
CXM MIC(mg/L) ≤4 >8 ≤4 8 ≥16 ≤1 2 > 2
CAZ MIC(mg/L) -# -# ≤2 -# -# -# -# -#
FEP MIC(mg/L) ≤4 >4 -# -# -# -# -# -#
CIP MIC(mg/L) ≤0.5 >0.5 ≤1 -# -# ≤0.5 > 0.5
ERY MIC(mg/L) ≤0.25 >0.5 ≤0.5 1–4 ≥8 ≤0.25 0.5 > 0.5
MEM MIC(mg/L) ≤2 >2 -# -# -# -# -# -#
TCY D-zone(mm) ≥28 <25 ≥29 25–28 ≤24 ≥22 ≤21
CHL D-zone(mm) ≥30 <30 -# -# -# -# -# -#
SXT D-zone(mm) ≥18 <15 ≥13 11–12 ≤10 ≥12 ≤11
  1. aMIC minimum inhibitory concentration, bD-zone diameter of inhibition zone, cEUCAST, European Committee on Antimicrobial Susceptibility Testing, dCLSI Clinical and Laboratory Standards Institute, eBSAC British Society for Antimicrobial Chemotherapy, *AMP ampicillin, AMC amoxicillin–clavulanic acid, CXM cefuroxime, CAZ ceftazidime, FEP cefepime, CIP ciprofloxacin, ERY eryciprofloxacin, MEM meropenem, TCY tetracycline, CHL chloramphenicol, SXT sulfamethoxazole–trimethoprim, # no breakpoints listed in the according criterion