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Table 1 Spearman correlation of biofilm species composition between generations in each lineage

From: Consistent and reproducible long-term in vitro growth of health and disease-associated oral subgingival biofilms

   All species Species > 0.1% abundance
Biofilm lineage Generations compared Spearman coefficient*† 95% CI Spearman coefficient*† 95% CI
lower upper lower upper
Healthy 1 1 vs 2 0.5050 0.4078 0.5908 0.6682 0.4603 0.8067
2 vs 3 0.6042 0.5204 0.6766 0.7532 0.5852 0.8592
3 vs 4 0.5644 0.4749 0.6424 0.8539 0.7445 0.9187
4 vs 5 0.6696 0.5961 0.732 0.9083 0.836 0.9496
5 vs 6 0.5167 0.421 0.6011 0.8649 0.7627 0.925
6 vs 7 0.5462 0.4541 0.6266 0.8875 0.8006 0.9379
7 vs 8 0.6155 0.5334 0.6862 0.9210 0.8581 0.9567
8 vs 9 0.6139 0.5314 0.6848 0.8953 0.8137 0.9423
9 vs 10 0.6239 0.543 0.6934 0.9286 0.8713 0.9609
1 vs 10 0.4580 0.3556 0.5496 0.5608 0.3132 0.737
Healthy 2 1 vs 2 0.4954 0.3971 0.5825 0.6761 0.4714 0.8116
2 vs 3 0.5083 0.4115 0.5937 0.7583 0.593 0.8623
3 vs 4 0.5863 0.4998 0.6612 0.8439 0.7281 0.9129
4 vs 5 0.6530 0.5768 0.718 0.8876 0.8006 0.9379
5 vs 6 0.5687 0.4798 0.6461 0.8599 0.7545 0.9221
6 vs 7 0.6336 0.5542 0.7016 0.9182 0.8532 0.9551
7 vs 8 0.6443 0.5666 0.7106 0.9497 0.9084 0.9726
8 vs 9 0.5907 0.5048 0.665 0.8961 0.8151 0.9427
9 vs 10 0.5827 0.4957 0.6582 0.8959 0.8148 0.9426
1 vs 10 0.3896 0.2806 0.4887 0.6559 0.4427 0.7989
Disease 2 1 vs 2 0.6508 0.5741 0.7161 0.7375 0.5616 0.8496
2 vs 3 0.7205 0.656 0.7746 0.9085 0.8364 0.9497
3 vs 4 0.7189 0.6541 0.7733 0.9560 0.9198 0.9761
4 vs 5 0.7559 0.6981 0.8039 0.9565 0.9207 0.9764
5 vs 6 0.7128 0.6469 0.7682 0.8019 0.6606 0.8883
6 vs 7 0.6978 0.6292 0.7557 0.7500 0.5803 0.8572
7 vs 8 0.6517 0.5753 0.7169 0.9215 0.8589 0.957
8 vs 9 0.7446 0.6846 0.7945 0.9137 0.8454 0.9526
9 vs 10 0.6835 0.6124 0.7437 0.9584 0.924 0.9774
1 vs 10 0.4775 0.3772 0.5668 0.4053 0.1195 0.6291
Disease 3 1 vs 2 0.7083 0.6415 0.7644 0.9005 0.8227 0.9452
2 vs 3 0.7489 0.6897 0.7981 0.9602 0.9272 0.9784
3 vs 4 0.6725 0.5994 0.7344 0.6996 0.5054 0.8263
4 vs 5 0.6971 0.6284 0.7551 0.9261 0.8669 0.9596
5 vs 6 0.6804 0.6087 0.7411 0.8171 0.6849 0.8973
6 vs 7 0.6639 0.5894 0.7272 0.7555 0.5888 0.8606
7 vs 8 0.6415 0.5633 0.7083 0.8654 0.7635 0.9253
8 vs 9 0.7485 0.6893 0.7978 0.9341 0.8808 0.964
9 vs 10 0.7567 0.6991 0.8046 0.9294 0.8727 0.9614
1 vs 10 0.5463 0.4543 0.6268 0.3555 0.0617 0.5925
  1. *Non-parametric p-value
  2. p = 0.001 for all unless otherwise indicated
  3. p < 0.05