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Fig. 7 | BMC Microbiology

Fig. 7

From: Lactic acid Bacteria isolated from European badgers (Meles meles) reduce the viability and survival of Bacillus Calmette-Guerin (BCG) vaccine and influence the immune response to BCG in a human macrophage model

Fig. 7

NF-κB activation in PMA-differentiated THP-1 macrophages exposed to inactivated cells from badger LAB isolates with no (or very low) pro-inflammatory (a) or pro-inflammatory (b) profile, in the absence (white bars) or presence (black bars) of BCG at a ratio of 100:10:1 (LAB:BCG:macrophage) for 6 h. A medium-only condition (RPMI) was included as a control. Comparative statistical analysis was carried out between BCG and all the LAB-BCG combinations using the Student t-test (*p < 0.05, **p < 0.01, ***p < 0.005). Data are mean ± SD representing three biological replicates each

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BMC Microbiology

ISSN: 1471-2180

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