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Fig. 6 | BMC Microbiology

Fig. 6

From: Lactic acid Bacteria isolated from European badgers (Meles meles) reduce the viability and survival of Bacillus Calmette-Guerin (BCG) vaccine and influence the immune response to BCG in a human macrophage model

Fig. 6

NF-κB activation in PMA-differentiated THP-1 macrophages exposed to inactivated cells of Lactobacillus reuterii D4, BCG and combinations of D4 with BCG (D4:BCG) for 24 h. When the bacteria were tested on their own, macrophages were exposed to bacteria at a bacteria:macrophage ratio of 100:1 (black dots); 10:1 (grey dots); and 1:1 (white dots); for the D4:BCG combinations, the macrophages were challenged with bacteria at a LAB:BCG:macrophage ratio of 100:100:1 (back dots); 100:10:1 (grey dots); and 100:1:1 (white dots). NF-κB activation is presented as a fold increase over a non-stimulated condition and data represent at least two biological replicates

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