Beta-defensin derived cationic antimicrobial peptides with potent killing activity against gram negative and gram positive bacteria

Table 1 The characteristics of newly designed CAMPs

Peptide^a	Amino acid sequence	Length (aa)	Molecular Weight	Charge	Hydrophobicity
CAMP-t1	RKFLRRRGEVAHFSQKSLGLYCWWW	25	3251.84	+ 4	44%
CAMP-t2	PIHRRIPPRWPRLKRRW	17	2361.90	+ 7	29%
CAMP-A	LRRLKPLIRPWLRPLRRWWW	20	2839.55	+ 7	50%
CAMP-B	RRRWRKRRWWW	11	1869.24	+ 7	36%

^aCAMP-t1, CAMP-t2, and CAMP-B are coated with a Trp-tail. N-terminal acetylation and C-terminal amidation were introduced to all peptides

ISSN: 1471-2180