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Table 2 Prevalence of CoNS resistance to different antimicrobial agents in Ethiopia

From: Prevalence and antimicrobial resistance of coagulase negative staphylococci clinical isolates from Ethiopia: a meta-analysis

 

Antimicrobial Agent

Frost plot presented in

No. of studies

No. of isolate tested

No. of resistant isolate

Pooled AMR Proportion (95% CI)

I2 (p-value)

1.

Methicilin

S1

9

317

140

0.37 (0.21,0.55)

88.70 (P ≤ 0.01)

2.

Vancomycin

S2

7

169

24

0.11 (0.00,0.35)

92.54 (P ≤ 0.01)

3.

Penicillin

S3

14

389

225

0.57 (0.40,0.73)

89.60 (P ≤ 0.01)

4.

Amoxicillin

S4

9

198

81

0.42 (0.23,0.61)

84.37 (P ≤ 0.01)

5.

Amoxicillin-clavulanate

S5

5

120

33

0.27 (0.02,0.65)

93.77 (P ≤ 0.01)

6.

Ampicillin

S6

13

338

216

0.64 (0.46,0.80)

89.92 (P ≤ 0.01)

7.

Tetracycline

S7

15

388

239

0.60 (0.49,0.70)

76.30(P ≤ 0.01)

8.

Doxycycline

S8

6

162

63

0.36 (0.19,0.55)

81.18(P ≤ 0.01)

9.

Sulfametaxazole-trimethoprim

S9

16

413

207

0.50 (0.36,0.64)

86.95(P ≤ 0.01)

10.

Ceftriaxone

S10

14

317

95

0.27 (0.18,0.38)

71.91 (P ≤ 0.01)

11.

Cephalothin

S11

5

61

23

0.32 (0.07,0.62)

78.01 (P ≤ 0.01)

12.

Norfloxacin

S12

8

177

58

0.39 (0.24,0.56)

74.57 (P ≤ 0.01)

13.

Chloramphenicol

S13

12

311

141

0.40 (0.23,0.58)

88.94(P ≤ 0.01)

14.

Clindamycin

S14

5

209

39

0.11 (0.02,0.27)

85.72 (P ≤ 0.01)

15.

Ciprofloxacin

S15

13

316

51

0.14 (0.06,0.22)

73.49 (P ≤ 0.01)

16.

Gentamicin

S16

17

431

123

0.27 (0.19,0.36)

69.04 (P ≤ 0.01)

17.

Erythromycin

S17

16

413

138

0.30 (0.20,0.42)

81.12 (P ≤ 0.01)