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Table 2 Reduced killing of mutacin IV and V indicator strains in the presence of erinacine C

From: Screening for inhibitors of mutacin synthesis in Streptococcus mutans using fluorescent reporter strains

  Treatment
Indicator strain control + Erinacine C + MIP + Erinacine C + MIP
Streptococcus sanguinis 162 ± 24 106 ± 9 239 ± 31 128 ± 12
Lactococcus lactis 121 ± 13 71 ± 8 168 ± 24 66 ± 6
  1. Erinacine C was provided to S. mutans at 5 μg/ml final concentration, and MIP at 2.5 μg/ml final concentration. S. sanguinis is a specific indicator stain for mutacin IV, and Lactococcus lactis for mutacin V. See Methods for details on overlay assay. The area of the zone of inhibition was calculated and the data are mean and standard deviation of three biological replicates