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Table 1 Prescreening results for suppressors of mutacin VI transcription

From: Screening for inhibitors of mutacin synthesis in Streptococcus mutans using fluorescent reporter strains

Compound

% fluorescence

Structure

References

t1

t2

t3

Erinacine C

43

38

40

[47]

Noricumazol A

33

29

24

[42, 54, 55]

Myxovirescin D

26

18

13

[43]

Chondrochloren B

47

38

25

[56, 57]

Aurachin A

40

26

16

[44, 58, 59]

Myxopyronin A

23

20

27

[45, 60,61,62]

Jerangolid E

42

42

35

[46, 63]

  1. Compounds that reduced fluorescence of the mutacin VI reporter at three time points (t1, t2, t3) by more than 50% without affecting growth (less than 10% reduction in OD600) are shown here. The total number of tested compounds was 297