Skip to main content

Table 6 Prevalence and mutation profile in rpoB, katG, inhA and ahpC genes in MDR strains in Kyrgyzstan

From: Mutations of rpoB, katG, inhA and ahp genes in rifampicin and isoniazid-resistant Mycobacterium tuberculosis in Kyrgyz Republic

MDR -TB N = 157 %
RIF-resistance INH-resistance
rpoB katG inhA ahpC
Ser531 → Leu Ser315 → Thr 79 50.3
Ser531 → Leu Ser315 → Thr InhA_T15 3 1.9
Ser531 → Leu Ser315 → Asn 5 3.2
Ser531 → Leu Ser315 → Arg 3 1.9
His526 → Arg Ser315 → Thr 7 4.5
His526 → Asp Ser315 → Thr 6 3.8
His526 → Tyr Ser315 → Thr InhA_T15 14 9.0
His526 → Leu Ser315 → Gly 1 0.6
His526 → Leu InhA_T15 2 1.3
His526 → Pro inhA_T15 1 0.6
His526 → Asn inhA_T15 1 0.6
Asp516 → Tyr Ser315 → Thr 13 8.3
Asp516 → Val Ser315 → Thr 2 1.3
Leu511 → Pro Ser315 → Thr 12 7.6
Leu533 → Pro Ser315 → Thr 8 5.1