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Table 3 Characteristics of patients with carbapenemase-producing Enterobacteriaceae

From: Carbapenemase-producing Enterobacteriaceae in Mexico: report of seven non-clonal cases in a pediatric hospital

Data

Cases

1

2

3

4

5

6

E. coli

K. pneumoniae

E. coli

K. pneumoniae

K. oxytoca

E. coli

E. cloacae

OXA-232

NDM-1

KPC-2

OXA-48

NDM-1

NDM-1

Base diagnosis

AML-M2

Intestinal malrotation

KTWS

preB-ALL

Trisomy 21, Fallot Tetralogy

Complicated varicella

Immuno-compromised

Yes

No

No

Yes

Yes

No

Infection

Sepsis, Neutropenic colitis

Necrotizing fasciitis, SSI

Cellulitis, SSI

Abdominal sepsis

UTI

Necrotizing fasciitis

Sample

Blood, peritoneal liquid

Blood, wound drainage

Surgical wound drainage

Blood

Urine

Wound drainage

ID timea

10

8

22

39

157

9

Other hospital

No

Yes

No

No

No

Yes

PICU

Yes

Yes

Yes

Yes

Yes

No

MV

Yes

Yes

Yes

Yes

Yes

No

Surgery

No

Yes

Yes

Yes

Yes

Yes

CVC

Yes

Yes

Yes

Yes

Yes

No

TPN

No

Yes

Yes

Yes

Yes

No

Previous AB

      

 3GC (days)

No

Yes (2)

Yes (23)

Yes (3)c

Yes (7)

Yes (3)

 4CG (days)

Yes (1)

No

No

Yes (8)c

No

No

 Carbapenems

Yes (8)

Yes (18)

Yes (42)b

Yes (26)b

Yes (37)

Yes (29)b

 Colistin

No

No

No

No

Yes

No

 Definitive Tx

COL+MEM

MEM + LEV

MEM + AK

MEM + PTZ

NIT

COL+MEM

 LOS (days)

11

20

44

40

197

35

 ND

2

2

3

3

3

2

 DI

PICU

Surgery

PIDD

PIDD

PIDD

PIDD

 Evolution

Deceased

Deceased

Alive

Deceased

Alive

Alive

  1. Dx diagnosis, AML-M2 acute myeloid leukemia M2, KTWS Klippel-Trenaunay-Weber syndrome, preB-ALL pre-B acute lymphoblastic leukemia, SSI surgical site infection, UTI urinary tract infection, PICU pediatric intensive care unit, MV mechanical ventilation, CVC central venous catheter, TPN total parenteral nutrition, AB antibiotics, 3GC third generation cephalosporins, Tx treatment, LOS length of in-hospital stay, COL colistin, MEM meropenem, AK amikacin, PTZ piperacillin/tazobactam, NIT nitrofurantoin, ND number of clinical departments during hospitalization, DI Clinical department in which the isolate was obtained, PIDD Pediatric Infectious Diseases Department, aDays since admission to identification of the organism, bIsolation during meropenem treatment, cEscalating regimen
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BMC Microbiology

ISSN: 1471-2180

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