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Table 1 Comparison of two different methods of osmotic extraction of α-IFN2b, manual and automated microscale platform

From: Microtiter miniature shaken bioreactor system as a scale-down model for process development of production of therapeutic alpha-interferon2b by recombinant Escherichia coli

Type of osmotic shock extraction DCW α-IFN2b release Volume of sample
(g/L) (μg/L) (mL)
Automated 3.05 ± 0.08 49.2 ± 0.55 1
Manual 2.94 ± 0.12 48.8 ± 1.34 1
  1. The results of DCW and α-IFN2b release are the average of triplicate experiments