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Table 2 Antibacterial and cytotoxic activities of the extracts obtained from the 40 mixed cultures against the indicated multidrug resistant pathogens and human cancer cell lines

From: Use of a mixed culture strategy to isolate halophilic bacteria with antibacterial and cytotoxic activity from the Manaure solar saltern in Colombia

Extract Antibacterial Activity Cytotoxic Activitya (IC50 μg/mL)
B. subtilis MRSA VRE K. pneumoniae A549 SiHa L929
A1BM2–1 + > 100 > 100 > 100
A1SM2–2 + > 100 > 100 > 100
C6BM2–3 + > 100 > 100 > 100
C6SM2–4 + > 100 > 100 > 100
C8BM2–5 > 100 > 100 > 100
C8SM2–6 + > 100 > 100 > 100
A1BM4–7 > 100 > 100 > 100
A1SM4–8 > 100 > 100 > 100
C6BM4–9 > 100 > 100 > 100
C6SM4–10 > 100 > 100 > 100
C8BM4–11 > 100 > 100 > 100
C8SM4–12 > 100 > 100 > 100
A1BM7–13 + > 100 > 100 > 100
A1SM7–14 > 100 > 100 > 100
C6BM7–15 + > 100 > 100 > 100
C6SM7–16 + > 100 > 100 > 100
C8BM7–17 + > 100 > 100 > 100
C8SM7–18 > 100 > 100 > 100
A1BM5–19 > 100 > 100 > 100
A1SM5–20 + > 100 > 100 > 100
C8BM5–21 + > 100 > 100 > 100
C8SM5–22 > 100 > 100 > 100
A1BM6–23 > 100 > 100 > 100
A1SM6–24 + > 100 > 100 > 100
C6BM6–25 > 100 > 100 > 100
C6SM6–26 + > 100 > 100 > 100
C8BM6–27 + > 100 > 100 > 100
C8SM6–28 + > 100 > 100 > 100
A1SM1–29 + + > 100 > 100 > 100
A1BM1–30 + > 100 > 100 > 100
C6SM1–31 + > 100 > 100 > 100
C6BM1–32 + > 100 > 100 > 100
C8SM1–33 > 100 > 100 > 100
C8BM1–34 > 100 > 100 > 100
A1BM3–35 + > 100 > 100 > 100
A1SM3–36 + + 44.90 ± 3.77 > 100 > 100
C6BM3–37 + > 100 > 100 > 100
C6SM3–38 + > 100 > 100 > 100
C8BM3–39 + > 100 > 100 > 100
C8SM3–40 64.60 ± 4.91 > 100 > 100
  1. a> 100: IC50 value over 100 μg/mL are considered not cytotoxic [59]