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Table 6 Minimal inhibitory concentrations of the main metabolites from C. roseus extracts. Where the metabolite was not commercially available we tested the closest metabolite or precursor that was available

From: Antibiotic-resistant bacteria in the guts of insects feeding on plants: prospects for discovering plant-derived antibiotics

Bacterial strain Minimal inhibitory concentration [mg/mL]
vindoline loganin ajmalicine catharanthine
Escherichia coli 0.3 0.6 0.6 0.6
Escherichia coli (permeable) 0.15 0.3 0.6 0.3
Mycobacterium smegmatis 0.6 0.6 0.6 0.6
Pseudomonas aeruginosa 0.3 0.6 0.6 0.6
Staphylococcus aureus 0.3 0.6 0.6 0.6
Bacillus vietnamensis 0.3 0.6 0.6 1.25
Microbacterium paraoxydans 0.3 0.6 0.6 0.6
Rhizobium pusense 0.3 0.6 0.6 0.6