Table 3 Fractional Inhibitory Concentration (FIC) values for combined antibiotics as defined by CLSI standards
From: msaABCR operon is involved in persister cell formation in Staphylococcus aureus
FIC Index | USA300 LAC | msaABCR | Complementation | ||||||
|---|---|---|---|---|---|---|---|---|---|
FIC | FIC range | INT | FIC | FIC range | INT | FIC | FIC range | INT | |
DAP / RIF | 0.176 | 0.162–0.193 | SN | 0.079 | 0.07–0.08 | SN | 0.176 | 0.162–0.193 | SN |
VAN / RIF | 0.354 | 0.31–0.375 | SN | 0.27 | 0.187–0.375 | SN | 0.35 | 0.31–0.37 | SN |
LIN / RIF | 0.246 | 0.18–0.315 | SN | 0.13 | 0.002–0.3 | SN | 0.25 | 0.18–0.32 | SN |
DAP / GEN | 0.346 | 0.269–0.437 | SN | 0.54 | 0.52–0.56 | AD | 0.346 | 0.269–0.437 | SN |
VAN / GEN | 0.87 | 0.75–1.0 | AD | 0.87 | 0.75–1.0 | AD | 0.87 | 0.75–1.0 | AD |
LIN / GEN | 0.54 | 0.51–0.56 | AD | 0.511 | 0.507–0.515 | AD | 0.54 | 0.51–0.56 | AD |