Fig. 2

Distribution of functional categories of core gene families in the Lactococcus genus. Cluster of Orthologous Group (COG) functional classification description — Information Storage and Processing: [A] RNA processing and modification; [B] chromatin structure and dynamics; [J] translation, ribosomal structure, and biogenesis; [K] transcription; [L] replication, recombination, and repair. Cellular Processes and Signaling: [D] cell cycle control, cell division, chromosome partitioning; [M] cell wall/membrane/envelope biogenesis; [N] cell motility; [O] posttranslational modification, protein turnover, chaperones; [T] signal transduction mechanisms; [U] intracellular trafficking, secretion, and vesicular transport; [V] defense mechanisms; [W] extracellular structures; [Y] nuclear structure; [Z] cytoskeleton. Metabolism: [C] energy production and conversion; [E] amino acid transport and metabolism; [F] nucleotide transport and metabolism; [H] coenzyme transport and metabolism; [G] carbohydrate transport and metabolism; [I] lipid transport and metabolism; [P] inorganic ion transport and metabolism; [Q] secondary metabolites biosynthesis, transport, and catabolism. Poorly Characterized: [R] general function prediction only; [S] function unknown