Fig. 4

Induction time of platelet aggregation with S. gallolyticus subsp. gallolyticus strains. The PRPs of three volunteers (a-c) were inoculated with the indicated S. gallolyticus subsp. gallolyticus strains. The induction times of the strains to promote platelet aggregation in all three volunteers are summed up in panel d. The time to induce a detectable platelet aggregation was determined using light transmission aggregation (BORN method; n = 3), as described in Materials and Methods. Value obtained with a sample in which no platelet aggregation was induced is listed and set at 1800 s