Fig. 2

Induction of IL6 in a whole blood model of S. gallolyticus subsp. gallolyticus strains. IL6 concentration (mean and standard deviation) after inoculation for 6 (a), 24 (b) and 48 h (c) with the S. gallolyticus subsp. gallolyticus strains DSM16831, DSM13808, BAA-2069, LMG17956 and UCN34 in a whole blood model of three different volunteers (n = 2 per volunteer), determined as described in Materials and Methods. The averaged IL6 concentration of all three volunteers (black bars) was used to demonstrate significant differences between the isolates (Mann-Whitney test, **: p ≤ 0.005; *: p ≤ 0.05)