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Table 2 Minimal inhibitory concentration (MIC, mg/L) assessed for CSA-13, CSA-131, LL-37, MET and magnetic nanoparticles (MNP) including MNPs functionalized with tested antibacterial agents, assessed in different combination of media against two anaerobic bacteria strains

From: Anaerobic bacteria growth in the presence of cathelicidin LL-37 and selected ceragenins delivered as magnetic nanoparticles cargo

  

MIC [mg/L]

Strain

Medium used for MIC evaluation

Met

MNP@ Met

LL-37

MNP@ LL-37

CSA-13

MNP@ CSA13

CSA 131

MNP@ CSA 131

MNP

Bacteroides fragilis ATCC 25285

Brucella broth supplemented with 1 μg/ml vitamin K1, 5 μg/ml hemin and 5% laked sheep blood

1

2

>256

>256

>256

>256

128

128

>256

Prevotella oralis

Brucella broth supplemented with 1 μg/ml vitamin K1 and 5 μg/ml hemin

2

2

256

256

128

128

128

128

256