Skip to main content

Table 2 Minimal inhibitory concentration (MIC, mg/L) assessed for CSA-13, CSA-131, LL-37, MET and magnetic nanoparticles (MNP) including MNPs functionalized with tested antibacterial agents, assessed in different combination of media against two anaerobic bacteria strains

From: Anaerobic bacteria growth in the presence of cathelicidin LL-37 and selected ceragenins delivered as magnetic nanoparticles cargo

   MIC [mg/L]
Strain Medium used for MIC evaluation Met MNP@ Met LL-37 MNP@ LL-37 CSA-13 MNP@ CSA13 CSA 131 MNP@ CSA 131 MNP
Bacteroides fragilis ATCC 25285 Brucella broth supplemented with 1 μg/ml vitamin K1, 5 μg/ml hemin and 5% laked sheep blood 1 2 >256 >256 >256 >256 128 128 >256
Prevotella oralis Brucella broth supplemented with 1 μg/ml vitamin K1 and 5 μg/ml hemin 2 2 256 256 128 128 128 128 256