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Table 2 PICRUSt predicted functions of KEGG categories represented in obese group compared to normal group

From: Comparative analysis of gut microbiota associated with body mass index in a large Korean cohort

KO Functional Categories

Difference between means (95% CI)a

obese vs. normal

Adj. P valuesb

Level 2

Level 3

Metabolism of Cofactors and Vitamins

Porphyrin and chlorophyll metabolism

0.025 (0.014–0.037)

7.42 × 10−3

Nucleotide Metabolism

Purine metabolism

0.026 (0.014–0.037)

2.36 × 10−3

Energy Metabolism

Oxidative phosphorylation

0.020 (0.014–0.027)

1.33 × 10−7

Photosynthesis proteins

0.019 (0.012–0.025)

3.73 × 10−6

Photosynthesis

0.019 (0.012–0.025)

5.64 × 10−6

Enzyme Families

Peptidases

0.020 (0.011–0.029)

3.29 × 10−3

Amino Acid Metabolism

Histidine metabolism

−0.015 (−0.020–0.009)

1.39 × 10−4

Arginine and proline metabolism

−0.015 (−0.022–0.008)

9.83 × 10−3

Valine, leucine and isoleucine biosynthesis

−0.015 (−0.022–0.008)

2.72 × 10−5

Carbohydrate Metabolism

Glycolysis / Gluconeogenesis

−0.013 (−0.019–0.008)

6.39 × 10−6

Pyruvate metabolism

−0.022 (−0.030–0.015)

1.23 × 10−6

Immune System Diseases

Primary Immunodeficiency

0.204 (0.139–0.269)

3.21 × 10−7

Immune System

Antigen Processing and Presentation

0.068 (0.044–0.092)

7.26 × 10−6

NOD-like receptor signaling pathway

0.064 (0.049–0.080)

8.71 × 10−13

  1. Only significant (Adj. P < 0.05) level 3 functions for obese vs normal weight were included in this table
  2. aCompared the difference between the means of relative frequency (%) of functional trait in normal and obese groups
  3. bApplied by Bonferroni multiple comparison correction methods