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Table 2 PICRUSt predicted functions of KEGG categories represented in obese group compared to normal group

From: Comparative analysis of gut microbiota associated with body mass index in a large Korean cohort

KO Functional Categories Difference between means (95% CI)a obese vs. normal Adj. P valuesb
Level 2 Level 3
Metabolism of Cofactors and Vitamins Porphyrin and chlorophyll metabolism 0.025 (0.014–0.037) 7.42 × 10−3
Nucleotide Metabolism Purine metabolism 0.026 (0.014–0.037) 2.36 × 10−3
Energy Metabolism Oxidative phosphorylation 0.020 (0.014–0.027) 1.33 × 10−7
Photosynthesis proteins 0.019 (0.012–0.025) 3.73 × 10−6
Photosynthesis 0.019 (0.012–0.025) 5.64 × 10−6
Enzyme Families Peptidases 0.020 (0.011–0.029) 3.29 × 10−3
Amino Acid Metabolism Histidine metabolism −0.015 (−0.020–0.009) 1.39 × 10−4
Arginine and proline metabolism −0.015 (−0.022–0.008) 9.83 × 10−3
Valine, leucine and isoleucine biosynthesis −0.015 (−0.022–0.008) 2.72 × 10−5
Carbohydrate Metabolism Glycolysis / Gluconeogenesis −0.013 (−0.019–0.008) 6.39 × 10−6
Pyruvate metabolism −0.022 (−0.030–0.015) 1.23 × 10−6
Immune System Diseases Primary Immunodeficiency 0.204 (0.139–0.269) 3.21 × 10−7
Immune System Antigen Processing and Presentation 0.068 (0.044–0.092) 7.26 × 10−6
NOD-like receptor signaling pathway 0.064 (0.049–0.080) 8.71 × 10−13
  1. Only significant (Adj. P < 0.05) level 3 functions for obese vs normal weight were included in this table
  2. aCompared the difference between the means of relative frequency (%) of functional trait in normal and obese groups
  3. bApplied by Bonferroni multiple comparison correction methods