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Table 4 In vitro activity of antifungal drugs against biofilm forming cells

From: Diversity, in-vitro virulence traits and antifungal susceptibility pattern of gastrointestinal yeast flora of healthy poultry, Gallus gallus domesticus

Yeast species (No. of isolates) MIC (mg/ml) of biofilm forming cells
Fluconazole Amphotericin B Voriconazole Caspofungin
Interval MIC50 MIC90 GM Interval MIC50 MIC90 GM Interval MIC50 MIC90 GM Interval MIC50 MIC90 GM
C. albicans (5) 8–256 128 204.8 64 0.5–4 1 3.2 1.3 0.5–8 4 8 2.29 0.062–0.5 0.125 0.5 0.18
D. catenulata (4) 16–256 - - 45.2 0.5–8 - - 2 1–2 - - 1.18 0.125–0.5 - - 0.25
C. tropicalis (1) 128 - - - 16 - - - 1 - - - 8 - - -
D. hansenii (10) 8–512 33 166.4 42.4 0.5–16 1 5.2 1.62 0.125–4 0.5 1.3 0.65 0.125–1 0.5 0.5 0.37
S. catenata (7) 8–512 64 281.6 47.5 1–16 2 8 2.2 0.5–16 0.5 7 1 0.5–4 0.5 2.2 0.74
C. acidothermophilum (1) 128 - - - 1 - - - 8 - - - 0.0625 - - -
Trichosporon spp. (3) 16–256 - - 50.7 4–16 - - 6.3 0.5–1 - - 0.62 0.125–0.5 - - 0.31
G. candidum (4) 16–128 - - 53.8 1–2 - - 1.18 0.5–1 - - 0.59 0.125–1 - - 0.42
Cryptococus macerans (3) 8–32 - - 16 1–8 - - 2.5 1–8 - - 2 0.125–1 - - 0.39