Table 3 In vitro activity of antifungal drugs against planktonic cells
Species (No. of isolates) | MIC (μg/ml) of Planktonic cells | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fluconazole | Amphotericin B | Voriconazole | Caspofungin | |||||||||||||
Interval | MIC 50 | MIC 90 | GM | Interval | MIC50 | MIC90 | GM | Interval | MIC50 | MIC90 | GM | Interval | MIC 50 | MIC90 | GM | |
C. albicans (10) | 0.03–16 | 4.5 | 16 | 2 | 0.03–8 | 0.37 | 2.6 | 0.4 | 0.125–8 | 0.37 | 8 | 0.61 | 0.03–0.5 | 0.125 | 0.5 | 0.12 |
D. catenulata (8) | 0.5–16 | 5 | 16 | 3.3 | 0.06–16 | 0.25 | 4.9 | 0.27 | 0.125–0.5 | 0.5 | 0.5 | 0.29 | 0.0625–0.5 | 0.125 | 0.325 | 0.14 |
C. tropicalis (6) | 4–16 | 8 | 12 | 7.12 | 0.03–16 | 2.5 | 16 | 1 | 0.125–8 | 0.5 | 6 | 0.89 | 0.125–.25 | 0.125 | 0.25 | 0.15 |
D. hansenii (29) | 0.03–16 | 1 | 9.6 | 0.952 | 0.03–16 | 0.25 | 1 | 0.28 | 0.06–1 | 0.25 | 0.5 | 0.20 | 0.03–1 | 0.125 | 0.5 | 0.17 |
S. catenata (12) | 0.13–16 | 4 | 8 | 2.5 | 0.03–16 | 0.18 | 14.8 | 0.35 | 0.125–1 | 0.5 | 0.5 | 0.37 | 0.125–1 | 0.25 | 0.25 | 0.21 |
C. pintolopesii (2) | 0.03–8 | - | - | 0.49 | 0.03–1 | - | - | 0.17 | 0.125–0.5 | - | - | 0.25 | 0.5–0.5 | - | - | 0.5 |
C. parapsilosis (1) | 2 | - | - | - | 0.5 | - | - | - | 0.25 | - | - | - | 0.0625 | - | - | - |
C. acidothermophilum (3) | 8–16 | - | - | 12.7 | 0.03–0.25 | - | - | 0.09 | 0.062–4 | - | - | 0.39 | 0.031–0.125 | - | - | 0.06 |
Cryptococus macerans (3) | 0.5–1 | - | - | 0.79 | 0.13–0.5 | - | - | 0.31 | 0.5–4 | - | - | 1 | 0.0313–0.5 | - | - | 0.15 |
Trichosporon spp. (9) | 0.03–16 | 4 | 9.6 | 2.92 | 0.25–16 | 1 | 9.6 | 1.36 | 0.120.5 | 0.25 | 0.5 | 0.27 | 0.062–0.5 | 0.125 | 0.3 | 0.14 |
G. candidum (4) | 0.5–8 | - | - | 2 | 0.03–2 | - | - | 0.29 | 0.125–0.5 | - | - | 0.29 | 0.031–0.25 | - | - | 0.14 |
Cystobasidium minuta (1) | 1 | - | - | - | 0.125 | - | - | - | 0.25 | - | - | - | 0.125 | - | - | - |