Table 1 Genetic variations among the NDM-1 and its variants and its first source of spread
NDM-1 variants | Amino acid(s) substitution | Source organism(s) |
|---|---|---|
NDM-2 | Proline 28 to Alanine | Acinetobacter baumannii |
NDM-3 | Aspartate 95 to Asparagine | Escherichia coli |
NDM-4 | Methionine 154 to Leucine | Escherichia coli |
NDM-5 | Valine 88 to Leucine Methionine 154 to Leucine | Escherichia coli |
NDM-6 | Alanine 233 to Valine | Escherichia coli |
NDM-7 | Aspartate 130 to Asparagine Methionine 154 to Leucine | Escherichia coli |
NDM-8 | Aspartate 130 to Glycine Methionine 154 to Leucine | Escherichia coli |
NDM-9 | Glutamic Acid 152 to Lysine | Klebsiella pneumoniae |
NDM-10 | Arginine 32 to Serine, Glycine 36 toAspartic acid, Glycine 69 to serine, Alanine 74 to threonine, Glycine 200 to Arginine | Klebsiella pneumoniae |
NDM-11 | NA | Escherichia coli |
NDM-12 | Glycine 222 to Aspartic acid and Methionine 154 to Leucine | Escherichia coli |
NDM-13 | Aspartic acid 95 to Asparagine and Methionine 154 to Leucine | Escherichia coli |
NDM-14 | Aspartic acid 130 to Glycine | Acinetobacter lwoffii |
NDM-15 | Alanine 233 to valine Methionine 154 to Leucine | Escherichia coli |
NDM-16 | Arginine 264 to Histidine | Klebsiella pneumoniae |
NDM-17 | Valine 88 to Leucine, Methionine 154 to Leucine and Glutamic acid 170 to Lysine | Escherichia coli |