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Table 4 Selected gene products significantly differentially abundant proteins in the Nm ΔdprA mutant compared to the wildtype when identified by mass spectrometry

From: Comparative proteomic analysis of Neisseria meningitidis wildtype and dprA null mutant strains links DNA processing to pilus biogenesis

Genes Protein name/function Protein fold
change
 Cell division proteins
ftsA Cell cycle -7
ZipA cell septum assembly -24
lon Lon protease/cell cycle -22
ftsZ Cell cycle -12
minD Septum site-determining protein -11
 Proteins of core metabolism
 Glycolysis and TCA cycle
tpiA Fructose and mannose metabolism; Glycolysis -20.72
pgm Amino sugar and nucleotide sugar metabolism -19.52
cbbA Fructose and mannose metabolism; Glycolysis -10.60
icd Carbon fixation; Citrate cycle (TCA cycle) -8.59
gapA-2 Glyceraldehyde-3-phosphate dehydrogenase 5.70
argH Arginine and proline metabolism 8.34
argF Arginine and proline metabolism 12.90
 Electron transport chain
NMB1127 Oxidoreductase, short chain dehydrogenase -56
mqo Probable malate:quinone oxidoreductase -27
nuoI NADH-quinone oxidoreductase subunit I -16
nqrB Na(+)-translocating NADH-quinone reductase subunit B +9
NMB0994 Acyl-CoA dehydrogenase family protein -7
NMB0923 Cytochrome c -6
NMB1677 Cytochrome c5 -5
petC Ubiquinol cytochrome c reductase -3
kat Catalase -22
trxB Thioredoxin reductase -8
  1. The minus sign of the protein fold change indicates the less abundant whereas the positive sign denotes the more abundant proteins.