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Table 3 Prevalence of azithromycin-resistant (AzmR) and macrolide-inducible clindamycin resistant (iMLSB) S. aureus isolates over time and between treatment arms

From: Short-term increase in prevalence of nasopharyngeal carriage of macrolide-resistant Staphylococcus aureus following mass drug administration with azithromycin for trachoma control

Survey Total Resistant (%) Crude OR (95% CI) p-value Adjusted ORa (95% CI) p-value
Overtime
 AzmR
  CSS-1 414 37 (8.9) 1   1  
  CSS-2 417 142 (34.1) 5.26 (4.95–5.59) <0.001 5.28 (4.95–5.64) <0.001
  CSS-3 343 25 (7.3) 0.80 (0.45–1.42) 0.447 0.82 (0.47–1.42) 0.471
 iMLSB
  CSS-1 414 24 (5.8) 1   1  
  CSS-2 417 128 (30.7) 7.20 (3.77–13.76) <0.001 7.24 (3.72–14.1) <0.001
  CSS-3 343 20 (5.8) 1.01 (0.87–1.16) 0.933 1.03 (0.90–1.17) 0.673
Between treatment arms
 AzmR
  1× 375 6 (1.6) 1   1  
  3× 434 25 (7.3) 4.83 (1.46–16.06) 0.010 5.22 (1.49–18.34) 0.010
 iMLSB
  1× 375 3 (0.8) 1   1  
  3× 434 20 (5.8) 7.68 (1.80–32.84) 0.006 8.37 (1.89–37.14) 0.005
  1. aadjusted for age and gender