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Table 1 Score matrix of the 10 NLS-motifs in the 13 NLS-bearing protein families, considering length, diversity and origin of NLS-like motifs

From: Evolutionary gradient of predicted nuclear localization signals (NLS)-bearing proteins in genomes of family Planctomycetaceae

NLS motif length diversity origin
PRRRK 5 3 5.66
RKRKK 5 3 5.98
RPRRK 5 3 5.38
KRPRP 5 3 5.36
RKRRR 5 2 7.96
P.KKKRK 7 4 5.3
TKRS…M 8 11 5.14
KR.{10}KKKL 16 23 5.12
K[RK]{3,5}.{11,18}[RK]K.{2,3}K 25 38 8.54
[KR]{4}.{20,24}K{1,4}.K 31 58 11.4
  1. Note: ‘length’ means total amino acid number in NLS motif; ‘diversity’ refer to total amino acid types in a NLS motif, symbols as ‘.’ or ‘[]’ in NLS motif will be given an extra reward score (+1, + 0.5 respectively); ‘origin’ was used here to judge the potential evolutionary dominance of NLS motif through classification of the species accommodating the NLS motif. Taking Planctomycetaceae as control (score = 0), if one NLS motif is only found in non-planctomycete bacteria but not found in eukaryotic or Planctomycetaceae species, this NLS motif will be regarded as having low evolutionary dominance, and its scored will be punished (− 5) regardless of NLS motif abundance in these species. In contrast, if one NLS motif was detected in a eukaryotic species, it will obtain a reward score (+5), meanwhile, if the average abandance of the NLS motif in a eukaryotic species is high, that means, this NLS motif will have much higher evolutionary dominance, and it will be given an extra reward score (reward score = average abundance of the motif in eukaryotes/10)