Table 3 Two component signal transduction systems identified in the genome of different S. suis 2 strains

LiaS/LiaR

Cell wall Stress response, antimicrobial resistance

No

1

1

1

1

NisK/NisR

Lantibiotic production

No

1

1

-

-

SalK/SalR

Lantibiotic production

Yes

1

1

-

-

CiaH/CiaR

Competence and antibiotic susceptibility

No

1

1

1

1

YycF/YycG

Essential for growth

No

1

1

1

1

YxdK/BecR

antimicrobial resistance

No

2

2

2

2

VanR/VanS

Vancomycin resistance

No

1

1

1

1

YocF/YocG

Thermosensing

No

1

1

1

1

CsrR

Virulence

Yes

1

1

1

1

YesM/YesN

Unknown

No

1

1

-

1

Orphan rr of the LytR family

Regulation of murein hydrolase activity

No

2

2

1

2

RevS

Virulence

Yes

1

1

-

1

VirS/VirR

Virulence

Yes

1

1

-

1