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Fig. 2 | BMC Microbiology

Fig. 2

From: Genome-wide analysis of a avirulent and reveal the strain induces pro-tective immunity against challenge with virulent Streptococcus suis Serotype 2

Fig. 2

Circular representation of the 05HAS68 genome and in silico comparisons between S. suis genomes. a The outer circle shows the scale (bp). From in to out indicate that circle 1: GC-skew (blue: > 0; light coral: < 0), circle 2: G + C content (avg = 41%), circle 3: duplicated genes, circle 4: colinear blocks (blue: unique to strain68; purple: colinear with strain05), circle 5: unique genes (inner: on plus strand; outer: on minus strand), circle 6: gene density (avg = 85%, win_size = 5 kb; blue: below avg level; red: above avg level), circle 7: cds (color: see COG legend; inner: on plus strand; outer: on minus strand), circle 8: coordinates. b The 05HAS68, 98HAH33, and Sanger protein sets were compared using FASTA3. Numbers under the strain name indicate genes that are not shared with the other strains; values in parentheses are the number of proteins in each strain (excluding frame shifted and degenerated genes). Numbers in the intersections indicate genes shared by two or three strains. These are displayed in the color corresponding to the strains used as the query. Numbers in any given intersection are slightly different due to gene duplications in some strains. c Phylogenetic tree of S.suis serotype 2 strains based on genomic sequences. The CRISPR antiviral system of 05HAS68 (d) and 89/1591 (e). f Two-dimensional gel electrophoresis profile of silver stained whole-cell proteins from S.suis 2 strain 05HAS68 (a) and 05ZYH33 (b) grown to the mid-exponential phase. In the 3D image displayed, the important virulence proteins EF, MRP and SYL are indicated by color arrow grey, black and white

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