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Table 5 Anticancer activity (IC50 μg mL−1) of the extracts prepared from endophytic fungi isolated from M. citriodora against different human cancer cell lines

From: Diversity, Phylogeny, anticancer and antimicrobial potential of fungal endophytes associated with Monarda citriodora L.

 

Tissue

Colon

Lung

Prostate

Breast

S.NO.

Cell line type

HCT-116

A549

PC-3

T47D

 

Code

IC50 (μg mL−1)

1.

MC-8 L

38.0 ± 0.08a

24.3 ± 0.03

26.4 ± 0.06

19.7 ± 0.1a

2.

MC-14 L

<10 ± 0.0

<10 ± 0.0

<10 ± 0.0

<10 ± 0.0

3.

MC-18 L

9.0 ± 0.02a

4.8 ± 0.02b

27.7 ± 0.06a,b

19.6 ± 0.02

4.

MC-24 L

<10 ± 0.0

<10 ± 0.0

<10 ± 0.0

<10 ± 0.0

5.

MC-25 L

<10 ± 0.0

<10 ± 0.0

9.9 ± 0.02

12.7 ± 0.02

6.

MC-7 F

32.2 ± 0.2a

23.6 ± 0.02a,b

32.3 ± 0.04b

26 ± 0.04

7.

MC-14 F

62.8 ± 0.5a,b

<10 ± 0.0a,c

23.3 ± 0.02b

42.7 ± 0.3c

8.

MC-26 F

11.1 ± 0.01

<10 ± 0.0

11.7 ± 0.01

8.0 ± 0.02

 

Paclitaxel in nM

120 ± 0.2

<10 ± 0.0

65 ± 0.3

777 ± 0.1

  1. same letters as superscript depicts significant difference at P < 0.05 between IC50 values of two cell lines (Additional file 1: Figure S2)