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Table 5 Anticancer activity (IC50 μg mL−1) of the extracts prepared from endophytic fungi isolated from M. citriodora against different human cancer cell lines

From: Diversity, Phylogeny, anticancer and antimicrobial potential of fungal endophytes associated with Monarda citriodora L.

  Tissue Colon Lung Prostate Breast
S.NO. Cell line type HCT-116 A549 PC-3 T47D
  Code IC50 (μg mL−1)
1. MC-8 L 38.0 ± 0.08a 24.3 ± 0.03 26.4 ± 0.06 19.7 ± 0.1a
2. MC-14 L <10 ± 0.0 <10 ± 0.0 <10 ± 0.0 <10 ± 0.0
3. MC-18 L 9.0 ± 0.02a 4.8 ± 0.02b 27.7 ± 0.06a,b 19.6 ± 0.02
4. MC-24 L <10 ± 0.0 <10 ± 0.0 <10 ± 0.0 <10 ± 0.0
5. MC-25 L <10 ± 0.0 <10 ± 0.0 9.9 ± 0.02 12.7 ± 0.02
6. MC-7 F 32.2 ± 0.2a 23.6 ± 0.02a,b 32.3 ± 0.04b 26 ± 0.04
7. MC-14 F 62.8 ± 0.5a,b <10 ± 0.0a,c 23.3 ± 0.02b 42.7 ± 0.3c
8. MC-26 F 11.1 ± 0.01 <10 ± 0.0 11.7 ± 0.01 8.0 ± 0.02
  Paclitaxel in nM 120 ± 0.2 <10 ± 0.0 65 ± 0.3 777 ± 0.1
  1. same letters as superscript depicts significant difference at P < 0.05 between IC50 values of two cell lines (Additional file 1: Figure S2)