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Table 4 Anticancer activity of the extracts (100 μg mL−1) prepared from endophytic fungi isolated from M. citriodora

From: Diversity, Phylogeny, anticancer and antimicrobial potential of fungal endophytes associated with Monarda citriodora L.

  Tissue Lung Colon Breast Prostate
S.No. Cell line type A549 HCT116 MCF7 PC-3
  Code Conc (μg mL−1) Percent Growth inhibition
1 MC-1 L 100 13 ± 0.8 0 ± 0 13 ± 0.3 16 ± 0.5
2 MC-2 L 100 35 ± 1 22 ± 0.3 52 ± 0 10 ± 0
3 MC-3 L 100 33 ± 0.5 12 ± 0.4 20 ± 0.4 41 ± 0.4
4 MC-4 L*** 100 67 ± 1 65 ± 0.2 91 ± 0.2 79 ± 0.3
5 MC-5 L 100 0 ± 0 47 ± 0 76 ± 0 51 ± 0.4
6 MC-6 L 100 27 ± 0.5 35 ± 0.5 54 ± 0.5 56 ± 0.4
7 MC-8 L*** 100 98 ± 1 99 ± 0.4 94 ± 0.4 95 ± 0.4
8 MC-9 L 100 22 ± 0.8 10 ± 0.2 14 ± 0.3 48 ± 0.2
9 MC-10 L 100 47 ± 0 18 ± 0.4 45 ± 0.4 49 ± 0
10 MC-12 L 100 34 ± 1 29 ± 0.6 37 ± 0.2 58 ± 0
11 MC-14 L*** 100 96 ± 1 100 ± 0.2 94 ± 0.3 100 ± 0.2
12 MC-15 L 100 24 ± 0.8 51 ± 0.8 86 ± 0 59 ± 0.5
13 MC-16 L*** 100 59 ± 0 47 ± 0.2 88 ± 0.2 61 ± 0.2
14 MC-17 L 100 48 ± 1 23 ± 0 23 ± 0.5 25 ± 0
15 MC-18 L*** 100 100 ± 0 93 ± 0.5 100 ± 0.2 90 ± 0.2
16 MC-20 L*** 100 77 ± 1 82 ± 0.5 77 ± 0.2 63 ± 0.5
17 MC-24 L*** 100 77 ± 1 99 ± 0.4 88 ± 0.4 96 ± 0
18 MC-25 L*** 100 88 ± 1 100 ± 0.2 94 ± 0.3 99 ± 0.4
19 MC-13R 100 40 ± 1 20 ± 0.6 35 ± 0.2 50 ± 0.5
20 MC-20R 100 10 ± 1 1 ± 0.4 26 ± 0.2 5 ± 0
21 MC-7 F*** 100 83 ± 1 87 ± 0 92 ± 0.5 74 ± 0
22 MC-14 F*** 100 99 ± 0 100 ± 0.4 91 ± 0.5 100 ± 0
23 MC-17 F 100 53 ± 1 28 ± 0 0 ± 0 7 ± 0
24 MC-21 F 100 0 ± 0 8 ± 0.3 11 ± 0.3 17 ± 0
25 MC-22 F*** 100 84 ± 1 75 ± 0.3 88 ± 0.4 80 ± 0.2
26 MC-23 F 100 0 ± 0 9 ± 0.2 0 ± 0 33 ± 0.4
27 MC-25 F 100 45 ± 1 90 ± 0.2 77 ± 0 81 ± 0.6
28 MC-26 F 100 94 ± 0 87 ± 0.5 97 ± 0.5 91 ± 0.2
  Paclitaxel 1 μM 79 ± 1    
  5-Fluorouracil 20 μM   45 ± 0   
  Adriamycin 1 μM    46 ± 0.7  
  Mitomycin 1 μM     63 ± 0
  1. *** Highly Significant at P < 0.05