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Table 2 The minimum inhibitory concentration and minimum bactericidal concentration of AvBD analogues

From: Novel synthetic analogues of avian β-defensin-12: the role of charge, hydrophobicity, and disulfide bridges in biological functions

Bacteria
(strain)
E. coli
(ATCC 25922)
S. Typhimurium
(ATCC 14028)
P. aeruginosa
(ATCC 27853)
S. aureus
(ATCC 29213)
Defensins MIC-ls MBC-ls MIC MIC-ls MBC-ls MIC MIC-ls MBC-ls MIC MIC-ls MBC-ls MIC
AvBD-12-A1 8 32 N/A 32 128 N/A 32 256 N/A 256 >256 N/A
AvBD-12-A2 4 16 N/A 16 64 N/A 16 32 N/A 256 256 N/A
AvBD-12-A3 4 16 128 16 64 >256 8 16 >256 128 256 >256
AvBD-12-A4 128 >256 N/A 256 >256 N/A 256 >256 N/A >256 >256 N/A
AvBD-12-A5 64 256 N/A 256 >256 N/A 256 >256 N/A >256 >256 N/A
AvBD-12-A6 64 256 N/A 256 >256 N/A 256 >256 N/A >256 >256 N/A
AvBD-12/6 8 32 256 16 64 >256 64 256 >256 256 256 256
AvBD-6 4 16 128 16 64 >256 64 128 >256 256 256 256
AvBD-12 32 128 256 128 256 >256 128 >256 >256 256 256 >256