Decision criteria for MALDI-TOF MS-based identification of filamentous fungi using commercial and in-house reference databases

Normand, Anne-Cécile; Cassagne, Carole; Gautier, Magali; Becker, Pierre; Ranque, Stéphane; Hendrickx, Marijke; Piarroux, Renaud

doi:10.1186/s12866-017-0937-2

Table 4 Comparison of the 10 different algorithms tested on the 422 strains included in the assessment panel against the in-house reference database

From: Decision criteria for MALDI-TOF MS-based identification of filamentous fungi using commercial and in-house reference databases

Threshold		A	B1	B2	C1	C2	C3	D1	D2	D3	D4
LS 1.5	%accepted	90.97	93.35	81.00	92.64	91.69	73.63	94.54	94.30	88.36	72.45
	species PPV	0.80	0.81	0.82	0.83	0.83	0.85	0.82	0.82	0.82	0.83
	genus PPV	0.90	0.92	0.90	0.93	0.93	0.93	0.92	0.92	0.92	0.91
LS 1.6	%accepted	87.41	90.02	77.67	89.55	88.60	70.78	90.26	90.02	84.32	68.65
	species PPV	0.84	0.84	0.86	0.85	0.86	0.89	0.86	0.86	0.86	0.88
	genus PPV	0.94	0.95	0.94	0.96	0.96	0.96	0.97	0.97	0.97	0.96
LS 1.7	%accepted	81.95	85.27	73.16	85.99	85.27	68.17	87.41	87.17	81.47	65.80
	species PPV	0.89	0.89	0.91	0.89	0.89	0.92	0.89	0.89	0.89	0.92
	genus PPV	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00
LS 1.8	%accepted	76.96	81.00	71.97	79.33	78.86	65.56	81.71	81.47	77.20	64.61
	species PPV	0.89	0.89	0.91	0.90	0.91	0.92	0.90	0.90	0.90	0.92
	genus PPV	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00
LS 1.9	%accepted	68.88	74.11	67.46	70.78	70.31	61.28	74.11	73.87	70.55	60.57
	species PPV	0.90	0.89	0.90	0.90	0.91	0.92	0.89	0.89	0.89	0.91
	genus PPV	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00
LS 2.0	%accepted	56.77	63.18	57.72	63.18	62.71	55.58	63.66	63.42	61.28	55.11
	species PPV	0.92	0.91	0.92	0.91	0.92	0.92	0.91	0.91	0.91	0.91
	genus PPV	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00
LS 2.1	%accepted	43.47	50.36	46.08	49.64	49.41	43.94	50.59	50.36	48.93	44.18
	species PPV	0.94	0.92	0.93	0.92	0.93	0.93	0.92	0.92	0.92	0.92
	genus PPV	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00
LS 2.2	%accepted	29.69	35.15	32.30	33.02	32.78	29.93	34.44	34.20	33.97	31.12
	species PPV	0.95	0.93	0.93	0.92	0.93	0.94	0.92	0.92	0.92	0.92
	genus PPV	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00
LS 2.3	%accepted	14.25	18.29	17.34	16.86	16.86	16.15	18.05	18.05	18.05	17.34
	species PPV	0.95	0.95	0.95	0.93	0.93	0.93	0.92	0.92	0.92	0.92
	genus PPV	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00

% accepted: percentage of submitted strains that fulfilled the criteria for identification at either the genus or species level, depending on the applied threshold; species PPV: positive predictive value at the species level; genus PPV: positive predictive value at the genus level

Back to article page

ISSN: 1471-2180

Contact us

General enquiries: journalsubmissions@springernature.com

BMC Microbiology

Contact us