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Table 5 Proteins involved in biosynthesis and stress response

From: Proteomic analysis of enterotoxigenic Escherichia coli (ETEC) in neutral and alkaline conditions

Protein

Description

1DLC

2DLC

Regulation

Run

Matching

AccB

Acetyl-CoA carboxylase biotin carboxyl carrier

1.83

 

UP

1-3

Both

AccD

Acetyl-coenzyme A carboxylase carboxyl transferase

1.53

1.93

UP

2-3

Both

ClpA

ATP-dependent Clp protease ATP-binding subunit

0.66

 

DOWN

1-2

H10407

ClpB

ATP-dependent chaperone ClpB

0.50

0.48

DOWN

1-2/All

Top

CspE

Cold shock protein CspE

1.72

1.74

UP

2-3/1-2

Both

DdlA

D-alanine--D-alanine ligase

 

0.44

DOWN

1-3

Both

DnaK

Chaperone protein DnaK

0.63

0.59

DOWN

All

Both

ErfK

ErfK/YbiS/YcfS/YnhG family protein

0.64

 

DOWN

2-3

Top

FabB

3-oxoacyl-(Acyl carrier protein) synthase I

0.59

0.49

DOWN

All

Both

FabF

3-oxoacyl-[acyl-carrier-protein] synthase 2

0.61

 

DOWN

2-3

Both

GadA

Glutamate decarboxylase

0.18

0.06

DOWN

1-2/2-3

Both

GadB

Glutamate decarboxylase beta subunit

0.08

0.04

DOWN

All/2-3

H10407

GlmM

Phosphoglucosamine mutase

0.64

 

DOWN

1-3

Top

GlmS

Glutamine--fructose-6-phosphate aminotransferase

 

0.61

DOWN

All

Both

GlnS

Glutamine--tRNA ligase

0.52

 

DOWN

2-3

Both

Gmk

Guanylate kinase

0.42

 

DOWN

2-3

Both

GrcA

Autonomous glycyl radical cofactor

0.41

0.32

DOWN

All

H10407

GroEL

60 kDa chaperonin

2.62

2.79

UP

2-3

Both

GshB

Glutathione synthetase

 

0.46

DOWN

2-3

Both

HdeB

Acid stress chaperone HdeB

0.22

 

DOWN

2-3

Both

HdhA

7-alpha-hydroxysteroid dehydrogenase

0.27

 

DOWN

2-3

Both

HtpB

Chaperone protein HtpG

 

0.74

DOWN

1-3

Top

KatG

Catalase-peroxidase

 

1.90

UP

2-3

Both

LpxA

Acyl-UDP-N-acetylglucosamine O-acyltransferase

1.51

 

UP

2-3

Top

MsyB

SecY/secA suppressor protein

0.58

 

DOWN

2-3

Both

NapA

Periplasmic nitrate reductase

0.46

 

DOWN

1-3

Both

OsmB

Osmotically inducible lipoprotein E

0.46

0.36

DOWN

1-3/All

H10407

OsmE

DNA-binding transcriptional activator OsmE

0.46

0.36

DOWN

1-3/All

Top

OsmY

Osmotically-inducible protein Y

0.28

0.26

DOWN

All

Both

OtsA

Alpha,alpha-trehalose-phosphate synthase

0.67

 

DOWN

1-2

Both

Prs

Ribose-phosphate pyrophosphokinase

 

1.60

UP

2-3

Top

PurA

Adenylosuccinate synthetase

0.64

0.62

DOWN

All/2-3

Both

Skp

Chaperone protein skp

0.59

 

DOWN

2-3

Both

SspA

Glutathione S-transferase domain protein

0.66

0.55

DOWN

1-3

Both

YbaY

Glycoprotein/polysaccharide metabolism

0.21

 

DOWN

2-3

Top

  1. Fold changes are listed under 1D-LC and 2D-LC columns