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Table 5 Proteins involved in biosynthesis and stress response

From: Proteomic analysis of enterotoxigenic Escherichia coli (ETEC) in neutral and alkaline conditions

Protein Description 1DLC 2DLC Regulation Run Matching
AccB Acetyl-CoA carboxylase biotin carboxyl carrier 1.83   UP 1-3 Both
AccD Acetyl-coenzyme A carboxylase carboxyl transferase 1.53 1.93 UP 2-3 Both
ClpA ATP-dependent Clp protease ATP-binding subunit 0.66   DOWN 1-2 H10407
ClpB ATP-dependent chaperone ClpB 0.50 0.48 DOWN 1-2/All Top
CspE Cold shock protein CspE 1.72 1.74 UP 2-3/1-2 Both
DdlA D-alanine--D-alanine ligase   0.44 DOWN 1-3 Both
DnaK Chaperone protein DnaK 0.63 0.59 DOWN All Both
ErfK ErfK/YbiS/YcfS/YnhG family protein 0.64   DOWN 2-3 Top
FabB 3-oxoacyl-(Acyl carrier protein) synthase I 0.59 0.49 DOWN All Both
FabF 3-oxoacyl-[acyl-carrier-protein] synthase 2 0.61   DOWN 2-3 Both
GadA Glutamate decarboxylase 0.18 0.06 DOWN 1-2/2-3 Both
GadB Glutamate decarboxylase beta subunit 0.08 0.04 DOWN All/2-3 H10407
GlmM Phosphoglucosamine mutase 0.64   DOWN 1-3 Top
GlmS Glutamine--fructose-6-phosphate aminotransferase   0.61 DOWN All Both
GlnS Glutamine--tRNA ligase 0.52   DOWN 2-3 Both
Gmk Guanylate kinase 0.42   DOWN 2-3 Both
GrcA Autonomous glycyl radical cofactor 0.41 0.32 DOWN All H10407
GroEL 60 kDa chaperonin 2.62 2.79 UP 2-3 Both
GshB Glutathione synthetase   0.46 DOWN 2-3 Both
HdeB Acid stress chaperone HdeB 0.22   DOWN 2-3 Both
HdhA 7-alpha-hydroxysteroid dehydrogenase 0.27   DOWN 2-3 Both
HtpB Chaperone protein HtpG   0.74 DOWN 1-3 Top
KatG Catalase-peroxidase   1.90 UP 2-3 Both
LpxA Acyl-UDP-N-acetylglucosamine O-acyltransferase 1.51   UP 2-3 Top
MsyB SecY/secA suppressor protein 0.58   DOWN 2-3 Both
NapA Periplasmic nitrate reductase 0.46   DOWN 1-3 Both
OsmB Osmotically inducible lipoprotein E 0.46 0.36 DOWN 1-3/All H10407
OsmE DNA-binding transcriptional activator OsmE 0.46 0.36 DOWN 1-3/All Top
OsmY Osmotically-inducible protein Y 0.28 0.26 DOWN All Both
OtsA Alpha,alpha-trehalose-phosphate synthase 0.67   DOWN 1-2 Both
Prs Ribose-phosphate pyrophosphokinase   1.60 UP 2-3 Top
PurA Adenylosuccinate synthetase 0.64 0.62 DOWN All/2-3 Both
Skp Chaperone protein skp 0.59   DOWN 2-3 Both
SspA Glutathione S-transferase domain protein 0.66 0.55 DOWN 1-3 Both
YbaY Glycoprotein/polysaccharide metabolism 0.21   DOWN 2-3 Top
  1. Fold changes are listed under 1D-LC and 2D-LC columns