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Table 1 Comparison of serological diagnosis by the novel criteria of ELISA and the stanndard criteria of IF assay

From: Evaluation of a broad-ranging and convenient enzyme-linked immunosorbent assay using the lysate of infected cells with five serotypes of Orientia tsutsugamushi, a causative agent of scrub typhus

Patients   No1 No2 No3 No4 No5 No6 No7 No8 No9 No10 No11 No12 No13 No14 No15 No16 No17 No18 No19
ELISA IgM > Av + 3SD 1) + + + + + + + + + + - + + + + + + + +
Eelevation of antibody between paired sera 2) + + + + + + - + + + + - + + - + - + +
Diagonosis P 3) P P P P P P P P P P P P P P P P P P
IF IgM ≥80 + + + + + + + + + + - + + - + + + + +
Eelevation of antibody between paired sera + + + + + + - + - + + - + + - + + + +
Diagonosis P P P P P P P P P P P P P P P P P P P
  1. 1) IgM antibody elevation in acutephase sera, 2) ≥4 or more folds-elevation of antibody titer between paired sera, 3) P:positive