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Table 1 RAST- annotated genes associating with resistance to antibiotics and toxic compounds

From: Acanthamoeba containing endosymbiotic chlamydia isolated from hospital environments and its potential role in inflammatory exacerbation

RAST Subsystem Role (KEGG located number) Features
Copper homeostasis Copper-translocating P-type ATPase (EC 3.6.3.4) peg.608, peg.990, peg.1254
Cobalt-zinc-cadmium resistance Heavy metal RND efflux outer membrane protein, CzcC family peg.605
Cobalt-zinc-cadmium resistance protein peg.1410
Cobalt/zinc/cadmium efflux RND transporter, membrane fusion protein, CzcB family peg.606
Cobalt-zinc-cadmium resistance protein CzcA peg.607
Cation efflux system protein CusA peg.607
Resistance to fluoroquinolones DNA gyrase subunit B (EC 5.99.1.3) peg.2036
DNA gyrase subunit A (EC 5.99.1.3) peg.2037
Topoisomerase IV subunit B (EC 5.99.1.-) peg.888
Topoisomerase IV subunit A (EC 5.99.1.-) peg.889
Beta-lactamase Beta-lactamase (EC 3.5.2.6) peg.1027, peg.1665
Metal-dependent hydrolases of the beta-lactamase superfamily I peg.123
Multidrug Resistance Efflux Pumps RND efflux system, outer membrane lipoprotein, NodT family peg.1170
RND efflux system, membrane fusion protein CmeA peg.1631
RND efflux system, outer membrane lipoprotein CmeC peg.1629
Acriflavin resistance protein peg.521
Membrane fusion protein of RND family multidrug efflux pump peg.522
RND efflux system, inner membrane transporter CmeB peg.1630
Multidrug Resistance Efflux Pumps Multidrug and toxin extrusion (MATE) family efflux pump YdhE/NorM, homolog peg.1277