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Table 2 Effect of inhibitors on the hydrolysis of Abz-AAL-EDDnp by OpdA

From: YPTB3816 of Yersinia pseudotuberculosis strain IP32953 is a virulence-related metallo-oligopeptidase

Inhibitor

Relative activity (%)

P Value

None

100

-

Phosphoramidon

150 ± 66

0.3515

E-64

212 ± 129

0.2361

Bestatin

103 ± 31

1.0000

PMSF

148 ± 61

0.3053

AEBSF

82 ± 12

0.3262

Leupeptin

73 ± 7

0.1690

Antipain

28 ± 5

0.0008*

ALLN

1 ± 10

0.0004*

Chymostatin

4 ± 34

0.0077*

EGTA

3 ± 16

0.0175*

  1. A star (*) denotes statistically valid difference (P < 0.05) compared to control (no inhibitors)
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BMC Microbiology

ISSN: 1471-2180

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