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Table 1 Effect of inhibitors on the hydrolysis of Abz-NKPRRPQ-EDDnp by OpdA

From: YPTB3816 of Yersinia pseudotuberculosis strain IP32953 is a virulence-related metallo-oligopeptidase

Inhibitor

Relative activity (%)

P Value

None

100

 

Phosphoramidon

92 ± 9

0.5759

E-64

101 ± 3

1.0000

Bestatin

95 ± 22

0.7791

PMSF

92 ± 14

0.4685

AEBSF

99 ± 10

0.9252

Leupeptin

87 ± 8

0.4590

Antipain

31 ± 2

0.0002*

ALLN

45 ± 9

0.0127*

Chymostatin

39 ± 11

0.0028*

EGTA

73 ± 9

0.0228*

  1. A star (*) denotes statistically valid difference (P < 0.05) compared to control (no inhibitors)