Fig. 3

Schematic representation of the pdu and cbi-cob-hem clusters of L. coryniformis CRL 1001. The arrows represent genes involved in: synthesis of uroporphyrinogen III (dark grey), synthesis of cobinamide, lower ligand and cobalt transport (light grey), propanediol degradation (black) and pocR, a transcriptional regulator (white). On the simplified B₁₂ synthesis pathway scheme, genes encoding proteins involved in synthesis of coenzyme (full lines) and synthesis and transport of intermediaries (incomplete lines) are highlighted