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Table 2 The ratio of HCV core Ag to HCV RNA and the infectivity of culture medium recovered at 96-h p.t

From: Production of infectious HCV genotype 1b virus in cell culture using a novel Set of adaptive mutations

 

Time after transfection (96 hr)

Core Ag

RNA

Core Ag/RNA

FFU

Specific infectiveity

 

(fmol/L)

(molecules/mL)

(copies/mL)

(molecules/copy)

(/mL)

(FFU/mL)

TPF1-4B

5892.4

3.5E + 09

7.2E + 05

4926.7

35

4.9E-05

TPF1-M170T

42742.7

2.6E + 10

1.1E + 07

2427.5

1300

1.2E-04