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Table 3 Cytotoxicity of diselenides against Hela, HDF and NCTC2544 cell lines

From: Diphenyl diselenide derivatives inhibit microbial biofilm formation involved in wound infection

CC50 (mg/L)

9

10

11

10c

10d

10e

Hela

123.69

113.69

10.92

32.16

19.25

9.71

HDF

55.02

135.86

8.36

35.29

112.93

>250

NCTC2544

14.62

44.61

18.45

250.00

23.84

>250

  1. Cytotoxicity was tested by the determination of the cell ATP level by a bioluminescent method after 24 h of incubation. CC50 is the concentration required to reduce the live cell number by 50 % compared to the untreated controls. The CC50 values are reported as the means from two independent experiments performed in duplicate
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BMC Microbiology

ISSN: 1471-2180

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