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Fig. 6 | BMC Microbiology

Fig. 6

From: Structure-function analysis of Avian β-defensin-6 and β-defensin-12: role of charge and disulfide bridges

Fig. 6

Chemotactic activity of AvBD-6 and AvBD-12. Migration of chicken macrophage MQ-NCSU cells (a), mouse immature dendritic JAWSII cells (b), AvBD-6 pretreated JAWSII cells (c), and AvBD-12 pretreated JAWSII cells (d), CCR2-positve CHO-K1 cells (e), CCR6-positive CHO-K1 cells (f). fLMP and CCL20 are used as positive control for dendritic cells and CCR6-transfected CHO-K1 cells, respectively. Chemotactic activities of AvBD-6 (□) and AvBD-12 (■) were expressed as chemotactic index (C.I.): = the number of migrated cells induced by AvBD/the number of migrated cells in response to chemotactic buffer. Data are presented as means of five independent experiments ± SD (n = 5). Different letters indicate significant difference (*p < 0.05). Asterisks indicate significant difference (*p < 0.05, **p < 0.01)

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