The SAV1322 gene from Staphylococcus aureus: genomic and proteomic approaches to identification and characterization of gene function

Table 1 Representative genes differentially expressed in the WT and sav1322 mutant strains

Gene locus	Gene	Description	Function	Fold change in sav1322 mutant
SAV1147	sdhC	Succinate dehydrogenase cytochrome b-558		−1.65
SAV2123		Hypothetical protein		−1.64
SAV2124	murZ	UDP-N-acetylglucosamine 1-carboxylvinyl transferase	Cell wall biogenesis	−2.02
SAV2125	glmS	Glucosamine-fructose-6-phosphate aminotransferase	Cell wall biogenesis	−1.64
SAV0052	ermA	Adenine N-6-methyltransferase		1.55
SAV0522	ctsR	Transcriptional regulator CtsR	Stress response Transcription regulation	1.76
SAV0523		Hypothetical protein		2.01
SAV0524		ATP: guanido-phosphotransferase		1.92
SAV0525	clpC	ATP-dependent Clp protease ATP-binding subunit ClpC	Stress response	1.72
SAV0975	clpB	ClpB chaperone homologue	Stress response	2.13
SAV1350	citB	Aconitate hydratase	Tricarboxylic acid cycle	1.55
SAV1579	dnaJ	Chaperone protein DnaJ	Stress response	1.56
SAV1580	dnaK	Chaperone protein DnaK	Stress response	2.30
SAV1581	grpE	Heat shock protein GrpE	Stress response	3.96
SAV1582	hrcA	Heat-inducible transcriptional repressor	Stress response	3.16
SAV1799		Hypothetical protein		2.23
SAV2497		Putative membrane protein		1.82

ISSN: 1471-2180