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Table 3 Relationship of combined baicalein with cefotaxime and the mRNA level of resistant genes

From: Synergistic effects of baicalein with cefotaxime against Klebsiella pneumoniae through inhibiting CTX-M-1 gene expression

Group

Synergy

Non- synergy

P value

Inhibition(%)

Non- inhibition (%)

Inhibition(%)

Non- inhibition(%)

TEM mRNA

100(6/6)

0(0/6)

33.3(2/6)

66.7(4/6)

0.061

CTX-M-1 mRNA

100(5/5)

0(0/5)

25(1/4)

75(3/4)

0.048*

CTX-M-9 mRNA

100(5/5)

0(0/5)

75(3/4)

25(1/4)

0.444

  1. Based on the information in the Figs. 4, 5 and 6, the percentage of inhibited strains for each gene in synergy group and non-synergy group was compared using Fisher’s Exact Test with SPSS
  2. *p <0.05 statistically significant
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BMC Microbiology

ISSN: 1471-2180

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