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Table 3 Relationship of combined baicalein with cefotaxime and the mRNA level of resistant genes

From: Synergistic effects of baicalein with cefotaxime against Klebsiella pneumoniae through inhibiting CTX-M-1 gene expression

Group Synergy Non- synergy P value
Inhibition(%) Non- inhibition (%) Inhibition(%) Non- inhibition(%)
TEM mRNA 100(6/6) 0(0/6) 33.3(2/6) 66.7(4/6) 0.061
CTX-M-1 mRNA 100(5/5) 0(0/5) 25(1/4) 75(3/4) 0.048*
CTX-M-9 mRNA 100(5/5) 0(0/5) 75(3/4) 25(1/4) 0.444
  1. Based on the information in the Figs. 4, 5 and 6, the percentage of inhibited strains for each gene in synergy group and non-synergy group was compared using Fisher’s Exact Test with SPSS
  2. *p <0.05 statistically significant