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Table 1 MIC (μg/mL) of selected antibiotics against Staphylococcus aureus in a half MIC of levofloxacin (LVX) or oxacillin (OXA)

From: Phenotypic and genotypic characterisation of multiple antibiotic-resistant Staphylococcus aureus exposed to subinhibitory levels of oxacillin and levofloxacin

Antibiotic

S. aureus KACC 10778

S. aureus ATCC 15564

S. aureus CCARM 3080

 

Control

LVX

OXA

Control

LVX

OXA

Control

LVX

OXA

Ampicillin

0.25(S)

0.125

0.25

32(R)

8

4

256(R)

<1

16

Cefoxitin

2(S)

0.5

0.5

4(S)

1

0.25

>512(R)

<1

32

Ceftazidime

8(R)

2

4

16(R)

16

4

512(R)

4

128

Ceftriaxone

2(R)

1

1

4(R)

1

0.25

>512(R)

<2

512

Chloramphenicol

8(S)

8

4

8(S)

4

4

16(I)

4

8

Ciprofloxacin

0.5(S)

0.125

0.25

0.5(S)

0.25

0.125

32(R)

1

8

Gentamicin

1(S)

0.5

1

16(R)

2

1

>512(R)

128

256

Imipenem

2(S)

1

1

0.25(S)

1

1

>512(R)

8

>512

Levofloxacin

0.25(S)

–

0.125

0.25(S)

–

0.0625

32(R)

–

4

Meropenem

0.125(S)

0.0313

0.0313

0.125(S)

0.0625

0.0313

64(R)

<1

8

Norfloxacin

2(S)

0.5

1

1(S)

0.5

0.5

32(R)

2

8

Oxacillin

0.25(S)

0.0625

–

0.25(S)

0.125

–

>512(R)

<1

–

Streptomycin

8(R)

4

4

64(R)

32–16

4

128(R)

512

4

Tetracycline

0.5(S)

0.5

0.5

0.25(S)

0.25

0.25

64(R)

16

32

Vancomycin

2(S)

0.5

0.5

2(S)

0.5

0.5

2(S)

2

0.5