Skip to main content

Table 1 Evaluation of Secretion Leader Sequences

From: Recombinant expression of Chlamydia trachomatis major outer membrane protein in E. Coli outer membrane as a substrate for vaccine research

Secretion Leader Amino Acid Sequences rMOMP Surface Expression
Cm-MOMP CtD-MOMP CtE-MOMP
Native Cm-MOMP MKKLLKSVLAFAVLGSASSLHA + - -
Native CtD/CtE-MOMP MKKLLKSVLVFAALGSASSLQA ND - -
Shigella flexneri (SopA) MKSKFLVLALCVPAIFTTHA ND ND +
Salmonella enterica (PgtE) MKTHVIAVMIIAVFSESVYA ND ND +
Yersinia pestis (Pla) MKKSSIVATIITILSGSANA ND ND +
E. coli OmpP MQTKLLAIMLAAPVVFSSQEASA ND ND +
E. coli OmpA MKKTAIAIAVALAGFATVAQA + ND +
pectate lyase B of Erwinia carotovora CE (PelB) MKYLLPTAAAGLLLLAAQPAMA + + +
  1. ND: Not Determined