Fig. 6

PA4570, upstream of rsmW, resembles an RsmA/RsmN homolog. a Similarities in gene topology between RsmN and PA4570 upstream of RsmW. b Primary sequence alignment of P. aeruginosa RsmA, RsmN, and PA4570 demonstrating sequence similarities. RsmN and RsmA has 64 % similarity and 31 % identity in sequence. RsmN and PA4570 has 51 % similarity and 17 % identity in sequence. RsmA and PA4570 has 49 % similarity and 16.3 % identity in sequence. Conservation stringency of residues is depicted using symbols below. (*) Single, fully conserved residue; (:) Conservation of strong groups; (.) Conservation of weak groups. L4 and R44 residues important for RsmE binding to hcnA 5’-UTR are fully and strongly conserved in PA4570, respectively, and indicated in bold. Boxes indicate region 1 and region 2 of CsrA, RsmA, and RsmE homologs thought to mediate RNA binding